Nashed R S, Becker D A, Gustilo R B
Department of Orthopaedic Surgery, Hennepin County Medical Center, Minneapolis, MN, USA.
Clin Orthop Relat Res. 1995 Aug(317):19-28.
The authors reviewed 175 primary cementless Biologic Ingrowth Anatomic System stem total hip arthroplasties with average followup of 7 years for wear and osteolysis. Group I (24 hips: fixed titanium heads, cemented polyethylene cups) had a wear rate of 0.10 mm per year, and lysis of 0%. Group II (62 hips: fixed titanium heads, cemented metal-backed cups) had a wear rate of 0.13 mm per year, and lysis of 31%. Group III (15 hips: fixed titanium heads, cementless cups) had a wear rate of 0.25 mm per year, and lysis of 87%. Group IV (74 hips: modular cobalt chromium heads, cementless cups) had a wear rate of 0.17 mm per year, and lysis of 24%. Wear rate was associated with younger age and male patients, but not polyethylene thickness. Age, gender, weight, and component stability had no effect on osteolysis rates. Group III had the statistically highest osteolysis rate. Group I had the statistically lowest osteolysis rate. Therefore, features of cementless acetabular cups, such as the screw holes, roughness of the metal shell, and locking mechanism, may cause increased wear and osteolysis.
作者回顾了175例初次非骨水泥型生物固定解剖型系统柄全髋关节置换术,平均随访7年以观察磨损和骨溶解情况。第一组(24髋:固定钛头,骨水泥固定聚乙烯髋臼杯)每年磨损率为0.10毫米,骨溶解率为0%。第二组(62髋:固定钛头,骨水泥固定金属背衬髋臼杯)每年磨损率为0.13毫米,骨溶解率为31%。第三组(15髋:固定钛头,非骨水泥髋臼杯)每年磨损率为0.25毫米,骨溶解率为87%。第四组(74髋:组合式钴铬合金头,非骨水泥髋臼杯)每年磨损率为0.17毫米,骨溶解率为24%。磨损率与年轻患者和男性患者相关,但与聚乙烯厚度无关。年龄、性别、体重和假体稳定性对骨溶解率无影响。第三组的骨溶解率在统计学上最高。第一组的骨溶解率在统计学上最低。因此,非骨水泥髋臼杯的特征,如螺孔、金属杯壳粗糙度和锁定机制,可能会导致磨损增加和骨溶解。