Saeed Z A, Ramirez F C, Hepps K S, Cole R A, Graham D Y
Department of Medicine, Veterans Affairs Medical Center, Houston, Texas, USA.
Gastrointest Endosc. 1995 Jun;41(6):561-5. doi: 10.1016/s0016-5107(95)70191-5.
Endoscopic therapy is effective in securing hemostasis for bleeding ulcers, but bleeding recurs in 10% to 30% of patients. Prospective identification of patients at increased risk for rebleeding is requisite to reducing rebleeding rates. We previously developed a three-component scoring system that identifies patients at increased risk for rebleeding. In the present study, we prospectively validated our scoring system. Forty-seven men ranging in age from 23 to 95 years in whom endoscopic therapy for bleeding ulcers was successful were studied. Patients with pre-endoscopy scores greater than 5 or postendoscopy scores greater than 10 were stratified as high-risk, and patients with pre-endoscopy scores of 5 or less and post-endoscopy scores of 10 or less as low-risk. Twenty-six patients were categorized as high-risk and 19 as low-risk. All patients were followed until discharged from the hospital. The rebleeding rate for high-risk patients was 31% (8 of 26), compared with 0 for low-risk patients (p < .05). We conclude that our scoring system accurately predicts patients at increased risk for rebleeding after successful endoscopic therapy of bleeding ulcers.
内镜治疗在确保出血性溃疡止血方面是有效的,但10%至30%的患者会再次出血。前瞻性识别再出血风险增加的患者对于降低再出血率是必要的。我们之前开发了一种三成分评分系统,用于识别再出血风险增加的患者。在本研究中,我们对我们的评分系统进行了前瞻性验证。研究了47名年龄在23至95岁之间、内镜治疗出血性溃疡成功的男性患者。内镜检查前评分大于5或内镜检查后评分大于10的患者被分层为高危患者,内镜检查前评分5或更低且内镜检查后评分10或更低的患者为低危患者。26名患者被归类为高危,19名患者被归类为低危。所有患者均随访至出院。高危患者的再出血率为31%(26例中的8例),而低危患者为0(p < 0.05)。我们得出结论,我们的评分系统能够准确预测出血性溃疡内镜治疗成功后再出血风险增加的患者。