Hermes B, Haas N, Czarnetzki B M
Hautklinik, Medizinische Fakultät der Humboldt-Universität, Virchow-Klinikum, Berlin.
Hautarzt. 1995 Jul;46(7):490-3. doi: 10.1007/s001050050288.
Annular elastolytic giant cell granuloma is mostly found in middle aged women in skin areas exposed to sunlight. Our 17-year-old female patient had a widespread reddish-brown lesion on the abdomen that met the histological criteria for annular elastolytic giant cell granuloma. However, the clinical findings and the localization were uncommon. UV light was excluded as a trigger. Other, still unknown, factors that might change antigenicity of elastic fibres must be considered. Spontaneous resolution suggests a transient influence of such factors. Differential diagnosis includes skin disorders with elastolysis; discrimination especially from mid-dermal elastolysis is not well defined.
环状弹性组织溶解性巨细胞肉芽肿多见于中年女性暴露于阳光的皮肤部位。我们的17岁女性患者腹部有广泛的红棕色皮损,符合环状弹性组织溶解性巨细胞肉芽肿的组织学标准。然而,临床表现和皮损部位并不常见。紫外线被排除为诱发因素。必须考虑其他可能改变弹性纤维抗原性的未知因素。自发消退提示这些因素的短暂影响。鉴别诊断包括伴有弹性组织溶解的皮肤疾病;尤其是与真皮中部弹性组织溶解的鉴别尚不明确。