Breitkopf C, Suter L
Fachklinik Hornheide, Westfälische-Wilhelms-Universität, Münster.
Hautarzt. 1995 Jul;46(7):502-4. doi: 10.1007/s001050050291.
A 71-year-old woman suffered from pronounced erosion of her nose after soft X-ray therapy (total dose 28 Gy, half dose depth 10.5-11.5 mm). 5 weeks after the end of the irradiation no healing tendency was observed. This unusual clinical course was caused by a simultaneously existing pemphigus vulgaris that worsened after radiotherapy, presumably as a consequence of the release of epidermal antigens. In this case it is improbable that the pemphigus was induced by the radiotherapy, as has been reported on several occasions in the literature. However, this possibility cannot be entirely excluded.
一名71岁女性在接受软X线治疗（总剂量28 Gy，半剂量深度10.5 - 11.5 mm）后出现明显的鼻部糜烂。放疗结束5周后未观察到愈合趋势。这种不寻常的临床病程是由同时存在的寻常型天疱疮引起的，放疗后病情恶化，可能是表皮抗原释放的结果。在这种情况下，天疱疮由放疗诱发的可能性不大，尽管文献中曾有过几次相关报道。然而，这种可能性也不能完全排除。
