Ye Z, Kageshita T, Ishihara T, Ito S, Ono T
Department of Dermatology, Kumamoto University School of Medicine, Japan.
J Dermatol. 1995 May;22(5):370-5.
A 36-year-old Japanese female, in whom malignant melanoma was detected from symptoms of brain metastasis, died 7 months later. The serum levels of 5-S-Cysteinyldopa (5-S-CD) and intercellular adhesion molecule-1 (ICAM-1) correlated with the disease progression. These values may be useful markers of disease progression for malignant melanoma, because the material is easily, frequently, and non-invasively obtained at regular intervals.
一名36岁的日本女性因脑转移症状被检测出患有恶性黑色素瘤,7个月后死亡。血清中5-巯基半胱氨酸多巴(5-S-CD)和细胞间黏附分子-1(ICAM-1)的水平与疾病进展相关。这些数值可能是恶性黑色素瘤疾病进展的有用标志物,因为该物质易于定期、频繁且无创地获取。