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Tissue inhibitors of matrix metalloendopeptidases.

作者信息

Murphy G, Willenbrock F

机构信息

Department of Cell and Molecular Biology, Strangeways Research Laboratory, Cambridge, United Kingdom.

出版信息

Methods Enzymol. 1995;248:496-510. doi: 10.1016/0076-6879(95)48032-3.

DOI:10.1016/0076-6879(95)48032-3
PMID:7674941
Abstract
摘要

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Tissue inhibitors of matrix metalloendopeptidases.基质金属内肽酶组织抑制剂
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Role of TIMP and MMP inhibition in preventing connective tissue breakdown.基质金属蛋白酶组织抑制因子（TIMP）和基质金属蛋白酶（MMP）抑制在预防结缔组织分解中的作用。
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Leukemic cells (HL-60) produce a novel extracellular matrix-degrading proteinase that is not inhibited by tissue inhibitors of matrix metalloproteinases (TIMPs).白血病细胞（HL-60）产生一种新型的细胞外基质降解蛋白酶，该酶不受基质金属蛋白酶组织抑制剂（TIMPs）的抑制。
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