Melchior H
Klinik für Urologie, Städtische Kliniken Kassel.
Urologe A. 1995 Jul;34(4):329-33.
Voiding dysfunction in elderly patients is not a uniform disease entity. Diseases of the cerebrospinal system, metabolic imbalances, detrusor degeneration and bladder outlet obstruction or sphincter impairment can all result in disabilities such as urinary retention and/or urinary incontinence. Although the urodynamic pattern of an uninhibited neuropathic bladder resulting from a poorly functioning corticoreticular system may seem to be normal in these elderly subjects, many of them have lost control of the micturition reflex: the warning to void occurs suddenly at full bladder capacity, and the abrupt sensation that urination is imminent cannot be controlled appropriately. Classifying these symptoms under a simple common denominator, such a detrusor instability can be misleading, because the therapeutic approach in these patients should be more highly differentiate. Detrusor overactivity may be symptomatic and associated with curable diseases of the lower urinary tract, such as bladder outlet obstruction, urinary tract infection or bladder cancer. On the other hand, some of the underlying causes of so-called idiopathic detrusor overactivity have been disclosed recently by Elbadawi et al. (1993), relating detrusor impairment to detrusor degeneration characterized morphologically by a dysjunction pattern. In this setting, it cannot be overemphasized that better knowledge of the underlying disease will result in more successful treatment of the voiding disability in such patients. Urinary incontinence in elderly patients is not always due to an incompetent urinary sphincter, and urinary retention in this age group is not always the result of a bladder outlet obstruction.(ABSTRACT TRUNCATED AT 250 WORDS)
老年患者的排尿功能障碍并非一种单一的疾病实体。脑脊液系统疾病、代谢失衡、逼尿肌退变以及膀胱出口梗阻或括约肌损伤均可导致诸如尿潴留和/或尿失禁等功能障碍。尽管在这些老年患者中,由皮质网状系统功能不良导致的无抑制性神经源性膀胱的尿动力学模式看似正常,但他们中的许多人已失去对排尿反射的控制:当膀胱充满时,排尿警告会突然出现,而即将排尿的突然感觉无法得到适当控制。将这些症状归为一个简单的共同类别,如逼尿肌不稳定,可能会产生误导,因为这些患者的治疗方法应更具针对性。逼尿肌过度活动可能是有症状的,并与下尿路的可治愈疾病相关,如膀胱出口梗阻、尿路感染或膀胱癌。另一方面,Elbadawi等人(1993年)最近揭示了所谓特发性逼尿肌过度活动的一些潜在原因,将逼尿肌损伤与以分离模式为形态特征的逼尿肌退变联系起来。在这种情况下,必须强调的是,对潜在疾病有更深入的了解将使此类患者的排尿功能障碍得到更成功的治疗。老年患者的尿失禁并不总是由于尿道括约肌功能不全,而这个年龄段的尿潴留也并不总是膀胱出口梗阻的结果。(摘要截选至250字)