Nixdorff U, Stein R, Erbel R, Rupprecht H J, Spiecker M, Meyer J
II. Medizinische Klinik und Poliklinik, Johannes-Gutenberg-Universitätsklinikum, Mainz.
Z Kardiol. 1995 Jul;84(7):503-11.
In 43 patients (ages 55.8 +/- 9.0 years) with myocardial infarction treated with thrombolytic therapy presenting with one-vessel coronary artery disease, the monitoring-ECGs during PTCA (17.0 +/- 12.7 days after infarct) were analyzed. Patients with ST-segment deviations > or = 0.1 mV (group A, n = 33) were compared with those < 0.1 mV (group B, n = 10). To answer the question, if these ischemic signs might be interpreted as salvaged myocardium, parameters of infarct size were evaluated. The maximal CK-activity in group A was 867 +/- 567 IU/l, in group B 1452 +/- 992 IU/l (p < 0.05), whereas the maximal GOT-activity was 113 +/- 69 IU/l and 174 +/- 102 UI/l (p < 0.05). The number of pathologic segments of the ventriculographies in the acute phase were 9 +/- 2 and 14 +/- 3 (p < 0.05), shortly after PTCA, 12 +/- 2 and 16 +/- 2 (p = 0.06), and after 6 months, 11 +/- 4 and 13 +/- 1 (N.S.). At the same time points EDV was analyzed in both groups and revealed the following: 103 +/- 20 ml, 98 +/- 21 ml, 104 +/- 23 ml and 103 +/- 25 ml (N.S.), 101 +/- 21 ml (N.S.), 116 +/- 46 ml (N.S.).(ABSTRACT TRUNCATED AT 250 WORDS)
在43例（年龄55.8±9.0岁）接受溶栓治疗的单支冠状动脉疾病心肌梗死患者中，分析了PTCA期间（心肌梗死后17.0±12.7天）的监测心电图。将ST段偏移≥0.1mV的患者（A组，n = 33）与<0.1mV的患者（B组，n = 10）进行比较。为了回答这些缺血迹象是否可被解释为存活心肌的问题，评估了梗死面积参数。A组的最大CK活性为867±567IU/l，B组为1452±992IU/l（p<0.05），而最大GOT活性分别为113±69IU/l和174±102IU/l（p<0.05）。急性期心室造影的病理性节段数分别为9±2和14±3（p<0.05），PTCA后不久为12±2和16±2（p = 0.06），6个月后为11±4和13±1（无显著性差异）。同时对两组在相同时间点的舒张末期容积（EDV）进行分析，结果如下：103±20ml、98±21ml、104±23ml和103±25ml（无显著性差异），101±21ml（无显著性差异），116±46ml（无显著性差异）。（摘要截短于250字）
