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全膝关节置换术后回收血的细胞质量。比较32例患者的引流血与静脉血。

Cell quality of salvaged blood after total knee arthroplasty. Drain blood compared to venous blood in 32 patients.

作者信息

Dalén T, Broström L A, Engström K G

机构信息

Department of Orthopedics, Northern University Hospital, Umeå, Sweden.

出版信息

Acta Orthop Scand. 1995 Aug;66(4):329-33. doi: 10.3109/17453679508995555.

Abstract

We used the ConstaVac drainage retransfusion system in 32 patients operated on with cemented tricompartmental knee arthroplasty. The mean total postoperative bleeding was 1.1 L of which 0.7 L was retransfused within 8 hours postoperatively. Samples were taken from the venous blood and drain blood at 2 hours and 6-8 hours postoperatively. The drain blood had low counts for leukocytes and thrombocytes as compared to venous blood, and fibrinogen was almost absent. Incubation at room temperature slightly lowered glucose and pH which made the erythrocytes swell. There was a slight hemolysis in the drain blood at 2 hours. At 6-8 hours the shed blood was closer to normal, especially with regard to hemolysis, but there was a further decrease in glucose. Within this time, there was no change in acidity and no further swelling of the erythrocytes. No clinical adverse reactions were observed and we consider the observed cellular and chemical changes to be of little importance. The quality of filtered drain blood within the analyzed time limit is considered acceptable for clinical use.

摘要

我们对32例行骨水泥型全膝关节置换术的患者使用了ConstaVac引流回输系统。术后总出血量平均为1.1升,其中0.7升在术后8小时内被回输。分别于术后2小时以及6 - 8小时采集静脉血和引流血样本。与静脉血相比,引流血中的白细胞和血小板计数较低,且几乎不存在纤维蛋白原。在室温下孵育会使葡萄糖含量略有降低,pH值下降,导致红细胞肿胀。术后2小时引流血出现轻微溶血。在6 - 8小时时,引流血更接近正常状态,尤其是溶血方面,但葡萄糖含量进一步降低。在此期间,酸度没有变化,红细胞也没有进一步肿胀。未观察到临床不良反应,我们认为所观察到的细胞和化学变化不太重要。在分析的时间范围内,过滤后的引流血质量被认为可用于临床。

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