[急性感染性结肠炎的大肠黏膜病理形态学]
[Pathomorphology of the large intestinal mucosa in acute infectious colitis].
作者信息
Shcherbakov I T, Novikova A V, Gracheva N M, Charnyĭ A M, Partin O S, Avakov A A, Gavrilov A F, Fokin S N, Leont'eva N I, Blokhina T I
出版信息
Arkh Patol. 1995 May-Jun;57(3):23-7.
634 biopsies of distal colon mucosa from 393 patients with acute intestinal bacterial and viral infections were studied histologically, histochemically and morphometrically. Acute catarrhal or catarrhal-hemorrhagic inflammation was found regardless of the colitis etiology (Shigella, Salmonella, Campylobacter, rotavirus). The most pronounced inflammation was in shigellosis and minimal one in rotavirus infection. Marked eosinophilic infiltration of the epithelium and tunica propria was observed in colonic contamination with C. pylori. Correlation analysis between morphometric indices in shigellosis and salmonellosis revealed a decrease in the number of strong functional links and the appearance of new ones indicating morphofunctional derangement.
对393例急性肠道细菌和病毒感染患者的634份远端结肠黏膜活检标本进行了组织学、组织化学和形态计量学研究。无论结肠炎病因（志贺氏菌、沙门氏菌、弯曲杆菌、轮状病毒）如何，均发现急性卡他性或卡他性出血性炎症。志贺氏菌病炎症最明显，轮状病毒感染炎症最轻。幽门螺杆菌感染结肠时，上皮和固有层可见明显的嗜酸性粒细胞浸润。志贺氏菌病和沙门氏菌病形态计量指标的相关性分析显示，强功能联系数量减少并出现新的联系，表明存在形态功能紊乱。
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