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[成人特发性巨结肠壁内神经系统的变化]

[Changes in the intramural nervous system in idiopathic megacolon in adults].

作者信息

Basilova T I, Vorob'ev G I, Nasyrina T A

出版信息

Arkh Patol. 1995 May-Jun;57(3):28-30.

PMID:7677576
Abstract

The ganglions of the muscular-interic plexus were studied in 94 surgical adult patients with an "idiopathic" megacolon. Both congenital and acquired ganglion lesions were found. Hypogangliosis (58% of patients), hypergangliosis (12% of patients) and hypoplasia (3.5% of patients) are considered as congenital lesions. Acquired degenerative changes of the nervous cells in the ganglions of the intramural nervous system were observed in 26% of patients of this group. Ultrastructurally, some of the ganglioneurocyte lesions were of the reactive type, while the others of the destructive type.

摘要

对94例患有“特发性”巨结肠的成年外科患者的肌间神经丛神经节进行了研究。发现了先天性和后天性神经节病变。神经节减少(58%的患者)、神经节增多(12%的患者)和发育不全(3.5%的患者)被视为先天性病变。在该组26%的患者中观察到壁内神经系统神经节中神经细胞的后天性退行性变化。在超微结构上,一些神经节神经细胞病变为反应性类型,而其他的为破坏性类型。

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