RNA的金属生物化学。六氨合钴（Ⅲ）作为镁离子水合离子结合位点的探针。
Metallobiochemistry of RNA. Co(NH3)6(3+) as a probe for Mg2+(aq) binding sites.
作者信息
Cowan J A
机构信息
Evans Laboratory of Chemistry, Ohio State University, Columbus.
出版信息
J Inorg Biochem. 1993 Feb 15;49(3):171-5. doi: 10.1016/0162-0134(93)80002-q.
PMID:7679435
Abstract
Co(NH3)6(3+) may serve as a probe of outer sphere complexation by Mg(H2O)6(2+) with RNA. The number of metal binding sites may be quantitatively assessed by optical spectroscopy (55-130, depending on background [K+]). Novel coordination-induced features have been observed in circular dichroism spectra.
摘要
六氨合钴（III）离子[Co(NH₃)₆(³⁺)]可用作镁离子[Mg(H₂O)₆(²⁺)]与RNA形成外层络合物的探针。金属结合位点的数量可通过光谱学进行定量评估（根据背景钾离子浓度[K⁺]，范围在55至130之间）。在圆二色光谱中观察到了新的配位诱导特征。
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