Rubens R D
ICRF Clinical Oncology Unit, Guy's Hospital, London, U.K.
Eur J Cancer. 1993;29A(4):604-5. doi: 10.1016/s0959-8049(05)80162-5.
When the treatment of advanced cancer is palliative in intent, evaluation of quality of life is of paramount importance in judging the effectiveness of treatment. The balance between adverse effects (costs) and benefits has been particularly difficult to determine with cytotoxic drugs. An approach to this problem using medical audit is described. It has been found to be a reliable method which has demonstrate a highly significant correlation between achievement of objective regression and acquisition of benefit. The method is now undergoing corroboration by a prospective study.
当晚期癌症的治疗目的是姑息性治疗时，生活质量评估对于判断治疗效果至关重要。细胞毒性药物的不良反应（成本）与益处之间的平衡尤其难以确定。本文描述了一种使用医疗审计来解决这一问题的方法。已发现这是一种可靠的方法，它显示出客观缓解的实现与获得益处之间存在高度显著的相关性。该方法目前正在通过一项前瞻性研究进行验证。
