Eichfeld U, Gläser A, Schneider G, Kraus J, Pauer H J, Schwarz I
Chirurgische Klinik und Poliklinik, Martin-Luther-Universität Halle-Wittenberg.
Zentralbl Chir. 1993;118(2):63-8.
94 patients with malignant melanoma or soft tissue sarcoma of the extremities were submitted to isolated cytostatic limb perfusion. With palliative indication for treatment of malignant melanoma, the 5 year survival rate was 25% after perfusion with methotrexate and 50% after perfusion with melphalan. The adjuvant perfusion showed very good results, too. Furthermore, the authors report on their first experiences in regional cytostatic perfusion of soft tissue sarcoma and bone sarcoma.
94例四肢恶性黑色素瘤或软组织肉瘤患者接受了孤立性细胞毒性肢体灌注治疗。对于有姑息治疗指征的恶性黑色素瘤患者，甲氨蝶呤灌注后的5年生存率为25%，美法仑灌注后的5年生存率为50%。辅助灌注也显示出非常好的效果。此外，作者报告了他们在软组织肉瘤和骨肉瘤区域细胞毒性灌注方面的初步经验。
