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霍奇金淋巴瘤伴发中央桥脑髓鞘溶解症

Hodgkin's disease associated with central pontine myelinolysis.

作者信息

Chintagumpala M M, Mahoney D H, McClain K, Dreyer Z E, Fishman M A, Carrol C L, Steuber C P

机构信息

Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

出版信息

Med Pediatr Oncol. 1993;21(4):311-4. doi: 10.1002/mpo.2950210416.

Abstract

We describe a 12-year-old black male who presented with cervical lymphadenopathy, hepatosplenomegaly of 3 months duration, and ataxia and incoordination of recent onset. Hodgkin's disease, stage IVB, was diagnosed. An MRI of the head demonstrated a nonenhancing, well-defined pontine lesion. The pontine lesion and the associated neurologic symptoms were consistent with central pontine myelinolysis. Treatment of Hodgkin's disease resulted in complete remission and complete disappearance of the pontine abnormality.

摘要

我们描述了一名12岁的黑人男性,他出现颈部淋巴结病、持续3个月的肝脾肿大以及近期发作的共济失调和协调障碍。诊断为IVB期霍奇金病。头部MRI显示脑桥有一个无强化、边界清晰的病变。脑桥病变及相关神经症状与中央脑桥髓鞘溶解症相符。霍奇金病的治疗导致完全缓解,脑桥异常完全消失。

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Masked Hodgkin's disease: the pruriginous disguise.隐匿性霍奇金病:瘙痒性伪装。
Pediatr Hematol Oncol. 1996 May-Jun;13(3):293-4. doi: 10.3109/08880019609030830.
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MOPP, ABVD, or both to treat Hodgkin's disease.采用MOPP方案、ABVD方案或两者联合治疗霍奇金淋巴瘤。
N Engl J Med. 1993 Apr 8;328(14):1045; author reply 1045-6. doi: 10.1056/NEJM199304083281417.

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