Isa Kroon W A, De Castro Barbosa F, Abad Vivas-Perez J I, Robles García J E, Zudaire Bergera J J, Berián Polo J M
Departamento de Urología, Clínica Universitaria, Facultad de Medicina, Universidad de Navarra, Pamplona.
Actas Urol Esp. 1993 Feb;17(2):122-5.
Presentation of our experience on the clinico-pathological staging of clinically localized prostate cancer (PCa) in 38 patients undergoing staging lymphadenectomy, 34 of which were treated with radical prostatectomy. From total number of patients, 37% were correctly staged, 60% were under-staged and only 3% were over-staged. A total of 11 patients (29%) presented nodular metastasis at the time of lymphadenectomy. Out of the 34 patients undergoing radical prostatectomy, 10 (29%) had microscopical invasion of prostatic capsule and seminal vesicles infiltration. The likelihood of nodes affectation in patients with prostatic capsule invasion and seminal vesicles infiltration was 60% and 70%, respectively. Mean PSA was significantly higher in patients with advanced disease as compared to those with disease localized in the prostatic gland. Also, mean PSA was significantly higher in patients with prostatic capsule invasion and seminal vesicles infiltration. The analysis by logistic regression identified pre-operative PSA as the only variable significantly correlated to the patient's final pathological stage.
介绍我们对38例行分期淋巴结清扫术的临床局限性前列腺癌（PCa）患者的临床病理分期经验，其中34例接受了根治性前列腺切除术。在所有患者中，37%分期正确，60%分期过低，仅3%分期过高。共有11例患者（29%）在淋巴结清扫时出现结节性转移。在34例行根治性前列腺切除术的患者中，10例（29%）有前列腺包膜镜下浸润和精囊浸润。前列腺包膜浸润和精囊浸润患者淋巴结受累的可能性分别为60%和70%。与局限于前列腺的疾病患者相比，晚期疾病患者的平均前列腺特异性抗原（PSA）显著更高。此外，前列腺包膜浸润和精囊浸润患者的平均PSA也显著更高。逻辑回归分析确定术前PSA是与患者最终病理分期显著相关的唯一变量。
