Buisseret-Delmas C, Yatim N, Buisseret P, Angaut P
Laboratoire de Physiologie de la Motricité, CNRS-UR 14, Paris, France.
Neurosci Res. 1993 Mar;16(3):195-207. doi: 10.1016/0168-0102(93)90124-9.
The existence of an X zone (lateral to the A zone) and a CX subzone (lateral to the C1 subzone) was documented within the anterior lobe and lobule VI in cats and primates. On the basis of their respective efferent and climbing fibre (CF) afferent connections, delineation of these two cortical subdivisions has been investigated here, in the rat, using small injections of WGA-HRP in the cerebellar cortex. We observe that both X and CX are "fractured" into a rostral and a caudal compartment. The rostral compartment of the X zone extends over lobules IV, V and VI and its caudal compartment over lobules VIII, IX and X. The rostral compartment of the CX subzone seems to be restricted to lobules V and VI, its caudal compartment cannot be topographically distinguished, over lobules IX and X, from the caudal compartment of the X zone. The olivary afferents to the X zone and the CX subzone arise from the horizontal and vertical lamellae of the medial accessory olive: subnucleus a projects into the rostral compartment and lobule VIII of the X zone. Subnuclei b and c project into the rostral compartment of both X and CX. The dorsomedial cell column selectively projects onto the caudal compartment of both X and CX over the vestibulo-cerebellum. The corticonuclear projections of the X zone have been found within the junctional region between the nucleus medialis and the nucleus interpositus (NI), here defined as the interstitial cell groups (icg), the corticonuclear projections of the CX subzone within the medial NI. It is suggested that the icg correspond to clusters of neurones dissociated from the medial aspect of the NI. We therefore consider the X zone and CX subzone of the rat, on the basis of their corticonuclear efferents, as "medial C1" and "lateral C1" subzone, respectively, although both may be regarded as part of the A zone on the basis of their olivary afferents.
在猫和灵长类动物的前叶和小叶VI中，已证实存在一个X区（位于A区外侧）和一个CX亚区（位于C1亚区外侧）。基于它们各自的传出和攀爬纤维（CF）传入连接，本文在大鼠中使用小脑皮质内小剂量注射WGA - HRP的方法，对这两个皮质亚区进行了划分研究。我们观察到，X区和CX区都“断裂”为一个嘴侧区和一个尾侧区。X区的嘴侧区延伸至小叶IV、V和VI，其尾侧区延伸至小叶VIII、IX和X。CX亚区的嘴侧区似乎局限于小叶V和VI，其尾侧区在小叶IX和X上，在地形上无法与X区的尾侧区区分开来。X区和CX亚区的橄榄传入纤维起源于内侧副橄榄核的水平和垂直薄片：亚核a投射到X区的嘴侧区和小叶VIII。亚核b和c投射到X区和CX区的嘴侧区。背内侧细胞柱选择性地投射到前庭小脑上X区和CX区的尾侧区。已发现X区的皮质核投射位于内侧核和间位核（NI）之间的连接区域内，此处定义为间质细胞群（icg），CX亚区的皮质核投射位于内侧NI内。有人认为icg对应于从小叶NI内侧解离出来的神经元簇。因此，基于它们的皮质核传出纤维，我们将大鼠的X区和CX亚区分别视为“内侧C1”和 “外侧C1” 亚区，尽管基于它们的橄榄传入纤维，两者都可被视为A区的一部分。
