一年中不同时间连续输注促性腺激素释放激素对母羊的影响。
Effect of continuous infusion of gonadotrophin-releasing hormone in ewes at different times of the year.
作者信息
Shareha A M, Ward W R, Birchall K
出版信息
J Reprod Fertil. 1976 Mar;46(2):331-40. doi: 10.1530/jrf.0.0460331.
Gn-RH (3 mug/hr for 8 hr) evoked a surge of LH in ewes during the anoestrous season which was of similar peak height to that found at oestrus but of shorter duration. When Gn-RH was given on 3 consecutive days, the response was considerably reduced on the 2nd and 3rd day. Follicles grew as a result of Gn-RH infusion but peripheral plasma oestrogen concentration did not increase. During the anoestrous season 9/18 ewes ovulated but only 1/6 did so at mid-anoestrus. Mature follicles or a CL were found in 15/18 ewes that had increased peripheral plasma progesterone concentrations for 1-5 days (11 ewes) or 9-14 days (4 ewes). The concentrations of progesterone found were always lower than those observed during the normal cycle. In the breeding season 10/11 ewes ovulated but there was no evidence that the induced CL were maintained.
促性腺激素释放激素（8小时内每小时3微克）在母羊处于乏情季节时引发了促黄体生成素的激增，其峰值高度与发情期时相似，但持续时间较短。当连续3天给予促性腺激素释放激素时，第2天和第3天的反应明显减弱。由于输注促性腺激素释放激素，卵泡生长，但外周血浆雌激素浓度并未增加。在乏情季节，18只母羊中有9只排卵，但在乏情中期只有1/6的母羊排卵。在18只外周血浆孕酮浓度升高1 - 5天（11只母羊）或9 - 14天（4只母羊）的母羊中，发现有15只存在成熟卵泡或黄体。所发现的孕酮浓度始终低于正常周期中的浓度。在繁殖季节，11只母羊中有10只排卵，但没有证据表明诱导形成的黄体能够维持。
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