Kawakubo K, Ohyashiki K, Ohyashiki J H, Kuriyama Y, Iwabuchi A, Kimura N, Sugita K, Nakazawa S, Toyama K
First Department of Internal Medicine, Tokyo Medical College, Japan.
Leukemia. 1993 Jun;7(6):909-11.
We report here a patient with acute myeloid leukemia (AML) expressing both T- and B-lymphoid-associated antigens. The leukemia cells in this case had rearrangements of not only immunoglobulin heavy-chain but also T-cell-receptor beta- and delta-chain genes. Although a relatively large number of AML patients with lymphoid markers have been reported, only about a dozen AML patients expressing both T- and B-lymphoid markers have been reported so far.