Ohnoshi T, Hayashi K, Tagawa S, Saito S, Matsutomo S, Kawashima K, Kimura I
Second Department of Medicine, Okayama University Medical School, Japan.
Intern Med. 1993 Feb;32(2):152-5. doi: 10.2169/internalmedicine.32.152.
A case of common variable immunodeficiency (CVID) who developed non-Hodgkin's lymphoma (NHL) of the rectum is reported. A 22-year-old male student in whom CVID was diagnosed at 7 years of age was referred to our department for the treatment of rectal NHL. The patient had stage IE disease confined to the rectum after clinical diagnostic procedures. He was initially treated with radiation therapy alone, but a relapse soon occurred in the paraaortic lymph nodes. He was successfully treated with CHOP-Bleo chemotherapy and supplementation with immunoglobulin preparations. He has since remained free of NHL and infectious complications for over 30 months despite his persistent immunodeficiency.
报告了一例患普通可变型免疫缺陷（CVID）并发直肠非霍奇金淋巴瘤（NHL）的病例。一名22岁男性学生，7岁时被诊断为CVID，因直肠NHL转诊至我科治疗。经临床诊断程序后发现，该患者处于局限于直肠的IE期疾病。他最初仅接受放射治疗，但很快腹主动脉旁淋巴结出现复发。他通过CHOP - 博来霉素化疗及补充免疫球蛋白制剂得到成功治疗。尽管他持续存在免疫缺陷，但自那以后30多个月来一直未出现NHL及感染并发症。
