Collins D A, Tobias J H, Hill R P, Bourke B E
Department of Rheumatology, St George's Hospital, London.
Br J Rheumatol. 1993 Jun;32(6):518-20. doi: 10.1093/rheumatology/32.6.518.
We have successfully overcome severe neutropenia in an RA patient treated with gold salts, using granulocyte colony-stimulating factor (G-CSF), reducing the duration of neutropenia and risk of infection. The patient suffered no side effects, and use of G-CSF represents an important addition to the management of a life-threatening drug reaction.
我们成功地使用粒细胞集落刺激因子(G-CSF),使一名接受金盐治疗的类风湿关节炎患者的严重中性粒细胞减少症得到缓解,缩短了中性粒细胞减少的持续时间,并降低了感染风险。该患者未出现副作用,G-CSF的使用是对危及生命的药物反应管理的一项重要补充。