Slezak H, Arocker-Mettinger E
2. Augenklinik der Universität Wien.
Klin Monbl Augenheilkd. 1993 Mar;202(3):249-51. doi: 10.1055/s-2008-1045590.
Hitherto no attention was paid to the prebasal vitreous body in children with congenital aniridia. Obviously there are, at least occasionally, two remarkable anomalies of the anterior hyaloid membrane.
Two children (one 3 years and the other 4 years old) with congenital anirida were examined in supine position at a special slitlamp in general anaesthesia. Both children were healthy besides their ocular malformation; pregnancy and delivery were unremarkable.
Only the younger child showed bilaterally in symmetrical fashion a thin, circular, whitish ligament between lens zonulae and anterior hyaloid membrane (zonulo-vitreal ligament). The eyes of both children exhibited a circumferential simple detachment of the anterior hyaloid membrane in the region of the ciliary body.
At least sometimes, the congenital aniridia can be associated with anomalies of the anterior hyaloid membrane: 1. Obviously the circumferential simple ciliary detachment of the anterior hyaloid membrane corresponds with the loss of physiological cilio-vitreal fibril systems. 2. The zonulo-vitreal ligament might be formed during the fetal time as a surplus connection between lens zonulae and anterior hyaloid membrane.
迄今为止，先天性无虹膜患儿的前基底部玻璃体一直未受到关注。显然，至少偶尔会出现前玻璃体膜的两种显著异常。
对两名先天性无虹膜患儿（一名3岁，另一名4岁）在全身麻醉下于特殊裂隙灯下仰卧位进行检查。除眼部畸形外，两名患儿均健康；妊娠和分娩过程无异常。
仅年幼患儿双侧对称地在晶状体小带与前玻璃体膜之间出现一条薄的、圆形的、白色韧带（小带 - 玻璃体韧带）。两名患儿的眼睛在睫状体区域均表现出前玻璃体膜的环形单纯性脱离。
至少有时，先天性无虹膜可与前玻璃体膜异常相关：1. 显然，前玻璃体膜的环形单纯性睫状体脱离与生理性睫状 - 玻璃体纤维系统的缺失相对应。2. 小带 - 玻璃体韧带可能在胎儿期作为晶状体小带与前玻璃体膜之间多余的连接而形成。
