Roudot-Thoraval F, Pawlotsky J M, Deforges L, Girollet P P, Dhumeaux D
Département d'Epidémiologie, Hôpital Henri Mondor, Créteil, France.
Gut. 1993;34(2 Suppl):S55-6. doi: 10.1136/gut.34.2_suppl.s55.
In a study designed to assess the prevalence of antibodies to hepatitis C virus (HCV) in pregnant women, anti-HCV positivity in French pregnant women was twice as high as that found in French blood donors. Positive ELISA 2 results were confirmed by positive RIBA 2 in most subjects, and seven of nine RIBA 2 positive patients also tested positive for HCV-RNA by PCR. High rates of anti-HCV positivity were seen among immigrant pregnant women, partly because of false positive results with ELISA 2. RIBA 2 results suggested that the prevalence of HCV infection was not any higher in immigrant compared with French pregnant women.
在一项旨在评估孕妇丙型肝炎病毒(HCV)抗体患病率的研究中,法国孕妇的抗-HCV阳性率是法国献血者的两倍。大多数受试者的ELISA 2阳性结果通过RIBA 2阳性得到证实,9例RIBA 2阳性患者中有7例经PCR检测HCV-RNA也呈阳性。在移民孕妇中观察到较高的抗-HCV阳性率,部分原因是ELISA 2出现假阳性结果。RIBA 2结果表明,与法国孕妇相比,移民中HCV感染的患病率并没有更高。