采用一日高剂量甲氨蝶呤方案及亚叶酸钙解救成功治疗宫角妊娠。

Successful treatment of cornual pregnancy with 1-day high-dose methotrexate regimen and folinic acid rescue.

作者信息

Talmon R, Filmar S, Itskovitz-Eldor J

机构信息

Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel.

出版信息

Gynecol Obstet Invest. 1993;35(4):243-4. doi: 10.1159/000292709.

DOI:10.1159/000292709

PMID:7687231

Abstract

This report describes a woman with a cornual pregnancy, documented by laparoscopy and ultrasonography, who was successfully treated with a 1-day high-dose methotrexate regimen and folinic acid rescue. The serum beta-hCG level was 2,260 and increased to 3,060 IU/l on the 5th day after treatment before it fell precipitously to below 250 IU/l 15 days after methotrexate treatment. No side effects were experienced by the patient.

摘要

本报告描述了一名经腹腔镜检查和超声检查确诊为宫角妊娠的女性，她采用一日高剂量甲氨蝶呤方案及亚叶酸解救治疗成功。血清β-人绒毛膜促性腺激素（β-hCG）水平为2260，治疗后第5天升至3060IU/L，之后在甲氨蝶呤治疗15天后急剧降至250IU/L以下。患者未出现副作用。