• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The 12q13-q15 translocation breakpoints in pleomorphic adenoma and clear-cell sarcoma of tendons and aponeuroses are different from that in myxoid liposarcoma.

作者信息

Stenman G, Sahlin P, Mark J, Chaganti R S, Kindblom L G, Aman P

机构信息

Department of Oral Pathology, University of Gothenburg, Sweden.

出版信息

Genes Chromosomes Cancer. 1993 Jul;7(3):178-80. doi: 10.1002/gcc.2870070312.

DOI:10.1002/gcc.2870070312
PMID:7687873
Abstract

The transcription factor gene CHOP was recently shown to be rearranged in myxoid liposarcoma with t(12;16)(q13;p11). We have analyzed whether the CHOP gene is the target of rearrangements in pleomorphic adenoma and clear-cell sarcoma of tendons and aponeuroses with chromosome abnormalities of 12q13-q15. Restriction fragment analysis showed that the CHOP gene and its flanking sequences were not rearranged in any of these tumor types, indicating that the 12q translocation breakpoints in pleomorphic adenoma and clear-cell sarcoma are different from that in myxoid liposarcoma.

摘要

相似文献

1
The 12q13-q15 translocation breakpoints in pleomorphic adenoma and clear-cell sarcoma of tendons and aponeuroses are different from that in myxoid liposarcoma.
Genes Chromosomes Cancer. 1993 Jul;7(3):178-80. doi: 10.1002/gcc.2870070312.
2
Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11).伴有t(12;16)(q13;p11)的黏液样脂肪肉瘤中转录因子基因CHOP的重排
Genes Chromosomes Cancer. 1992 Nov;5(4):278-85. doi: 10.1002/gcc.2870050403.
3
No rearrangements of the CHOP gene in malignant fibrous histiocytoma.恶性纤维组织细胞瘤中CHOP基因无重排。
Cancer Genet Cytogenet. 1994 Feb;72(2):155-6. doi: 10.1016/0165-4608(94)90133-3.
4
Fusion of the EWS and CHOP genes in myxoid liposarcoma.黏液样脂肪肉瘤中EWS和CHOP基因的融合
Oncogene. 1996 Feb 1;12(3):489-94.
5
Chimeric TLS/FUS-CHOP gene expression and the heterogeneity of its junction in human myxoid and round cell liposarcoma.嵌合型 TLS/FUS-CHOP 基因表达及其在人黏液样和圆形细胞脂肪肉瘤中连接区的异质性
Am J Pathol. 1995 Nov;147(5):1221-7.
6
Physical mapping of chromosome 12q breakpoints in lipoma, pleomorphic salivary gland adenoma, uterine leiomyoma, and myxoid liposarcoma.脂肪瘤、多形性腺瘤、子宫平滑肌瘤和黏液样脂肪肉瘤中12号染色体q臂断点的物理图谱。
Genomics. 1994 Mar 15;20(2):210-22. doi: 10.1006/geno.1994.1155.
7
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma.在人类黏液样脂肪肉瘤中CHOP与一种新型RNA结合蛋白的融合。
Nature. 1993 Jun 17;363(6430):640-4. doi: 10.1038/363640a0.
8
Chromosome 12 breakpoints are cytogenetically different in benign and malignant lipogenic tumors: localization of breakpoints in lipoma to 12q15 and in myxoid liposarcoma to 12q13.3.12号染色体断点在良性和恶性脂肪生成性肿瘤中细胞遗传学上存在差异：脂肪瘤中的断点定位于12q15，黏液样脂肪肉瘤中的断点定位于12q13.3。
Cancer Res. 1993 Apr 1;53(7):1670-5.
9
A 6-Mb yeast artificial chromosome contig and long-range physical map encompassing the region on chromosome 12q15 frequently rearranged in a variety of benign solid tumors.一个包含12号染色体q15区域的6兆碱基酵母人工染色体重叠群和长程物理图谱，该区域在多种良性实体瘤中经常发生重排。
Genomics. 1995 Oct 10;29(3):665-78. doi: 10.1006/geno.1995.9952.
10
Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma.在恶性脂肪肉瘤中，通过12号和16号染色体易位（t(12;16)），显性负性转录调节因子CHOP与新基因FUS发生融合。
Nat Genet. 1993 Jun;4(2):175-80. doi: 10.1038/ng0693-175.

引用本文的文献

1
DNA amplifications at 20q13 and MDM2 define distinct subsets of evolved breast and ovarian tumours.20q13处的DNA扩增和MDM2可定义进展期乳腺癌和卵巢癌的不同亚组。
Br J Cancer. 1996 Dec;74(12):1984-9. doi: 10.1038/bjc.1996.664.
2
Chromosomal aberrations in soft tissue tumors. Relevance to diagnosis, classification, and molecular mechanisms.软组织肿瘤中的染色体畸变。与诊断、分类及分子机制的相关性。
Am J Pathol. 1994 Jun;144(6):1121-34.