Brandt R R, Dunn W F, Ory S J
Mayo Graduate School of Medicine, Rochester, Minn.
Chest. 1993 Aug;104(2):631-3. doi: 10.1378/chest.104.2.631.
Thirty-two percent dextran 70 is a highly viscous polysaccharide liquid used for uterine distention during hysteroscopy. Although generally safe, this agent has been recognized recently to cause noncardiogenic pulmonary edema, renal insufficiency, and intravascular coagulopathy. We report a case of acute 32 percent dextran 70 embolization, associated with intravascular coagulopathy, bilateral lung infiltrates, and rhabdomyolysis, recognized initially by hemoptysis and pleuritic chest pain while the patient was in the recovery room following a hysteroscopic procedure. Pulmonary, anesthesiology, and critical care physicians should be aware of these potential complications of hysteroscopic surgery.
32%的右旋糖酐70是一种高粘性多糖液体，用于宫腔镜检查时扩张子宫。尽管该药物一般安全，但最近已认识到它会导致非心源性肺水肿、肾功能不全和血管内凝血病。我们报告一例急性32%右旋糖酐70栓塞病例，伴有血管内凝血病、双侧肺部浸润和横纹肌溶解，最初是在宫腔镜手术后患者处于恢复室时，通过咯血和胸膜炎性胸痛发现的。肺科、麻醉科和重症监护医生应了解宫腔镜手术的这些潜在并发症。
