通过荧光原位杂交检测人类18号染色体的异态性。
Heteromorphism of human chromosome 18 detected by fluorescent in situ hybridization.
作者信息
Bonfatti A, Giunta C, Sensi A, Gruppioni R, Rubini M, Fontana F
机构信息
Institute of Medical Genetics USL 31, Ferrara, Italy.
出版信息
Eur J Histochem. 1993;37(2):149-54.
PMID:7688600
Abstract
The individual variations of pericentromeric heterochromatin in human chromosome 18 were analysed using the C-banding techniques and nonradioactive fluorescence in situ hybridization (FISH) with chromosome 18 alpha-satellite DNA probe. FISH analysis shows heteromorphisms almost undetectable by C-banding and which regularly segregate in a family.
摘要
采用C显带技术和用18号染色体α卫星DNA探针进行的非放射性荧光原位杂交（FISH）对人类18号染色体着丝粒周围异染色质的个体差异进行了分析。FISH分析显示了一些几乎无法用C显带检测到的异态，并且它们在一个家族中呈规律分离。
Zotero 插件