Vorob'ev A A, Khoroshko N V, Selezneva O Iu
Vestn Ross Akad Med Nauk. 1993(2):31-7.
The review covers the problems of environmental safety of industrial microbial strains derived by genetic engineering techniques and used to prepare biologically active substances. E. coli was used as an example to show the significance of studying their biological characteristics, taxonomy, interaction with other microorganisms and macroorganisms. Based on the data available in the literature it is concluded that there is a need to work out a set of measures to continuously monitor recombinant microorganisms used in biotechnological industry.
该综述涵盖了通过基因工程技术获得并用于制备生物活性物质的工业微生物菌株的环境安全问题。以大肠杆菌为例，展示了研究其生物学特性、分类学、与其他微生物及大型生物相互作用的重要性。基于文献中的现有数据得出结论，有必要制定一套措施，以持续监测生物技术产业中使用的重组微生物。
