Dodonova N Y
Institute of Physics, Photonics Department, University of St. Petersburg.
J Photochem Photobiol B. 1993 May;18(2-3):111-21. doi: 10.1016/1011-1344(93)80052-b.
The vacuum UV radiation absorbed by biomolecules may initiate luminescence, photodestruction and photoionization processes which lead to distortions or damage of the molecular structure. To explain the mechanisms of the processes in question and the role of different molecular fragments, it is necessary to analyse the absorption spectra. The accurate determination of the photoproducts is necessary when discussing the possible scission of molecular bonds. A knowledge of the quantum yields of vacuum UV-induced processes provides information on the relative effectiveness of different processes. In particular, the most efficient destruction of purine-pyrimidine bases, nucleotides and DNA is caused by irradiation of aqueous solutions rather than solid compounds. Additional information on molecular damage mechanisms may be obtained by comparison of data obtained using ionizing UV and UV laser irradiation.
生物分子吸收的真空紫外辐射可能引发发光、光破坏和光电离过程，这些过程会导致分子结构的扭曲或损伤。为了解释上述过程的机制以及不同分子片段的作用，有必要分析吸收光谱。在讨论分子键可能的断裂时，准确测定光产物是必要的。了解真空紫外诱导过程的量子产率可提供不同过程相对效率的信息。特别是，嘌呤 - 嘧啶碱基、核苷酸和DNA最有效的破坏是由水溶液而非固体化合物的辐照引起的。通过比较使用电离紫外和紫外激光辐照获得的数据，可获得有关分子损伤机制的更多信息。
