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阿霉素、VM26、环磷酰胺和泼尼松(AVmCP)联合治疗播散性淋巴网状肉瘤(III期或IV期或局部形态)

[Adriamycin, VM 26, cyclophosphamide and prednisone (AVmCP) combination in the therapy of disseminated lymphoreticulosarcoma (Stages or topographical forms III and IV].

作者信息

Misset J L, Pouillart P, Amiel J L, Schwarzenberg L, Hayat M, de Vassal F, Musset M, Belpomme D, Jasmin C, Albahary C, Depierre R, Mathé G

出版信息

Nouv Presse Med. 1975 Dec 20;4(44):3117-20.

PMID:768904
Abstract

This work presents the results obtained on 24 patients with disseminated lymphosarcoma and reticulosarcoma (stage III and IV) with a cyclic combination chemotherapy which combines adriamycin, epipodophyllotoxin (VM 26), cyclophosphamide and prednisone. The complete remission rate is 58 p.cent of the patients who entered the trial, the response rate is 75 p.cent. Tolerance of the regimen is good in general from the hematological point of view.

摘要

这项研究展示了对24例播散性淋巴肉瘤和网状细胞肉瘤(III期和IV期)患者采用阿霉素、表鬼臼毒素(VM 26)、环磷酰胺和强的松联合的周期性化疗方案所取得的结果。进入试验的患者完全缓解率为58%,有效率为75%。从血液学角度来看,该方案总体耐受性良好。

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