Lucsko M, Chaignon M, Guédon J
Nouv Presse Med. 1975 Dec 31;4(46 Suppl):3287-9.
Fifty hypertensive patients were given a beta-blocker, acebutolol, alone or in association with other hypotensive drugs, in an open therapeutic trial lasting for a year. The results of treatment were considered to be good or moderate in 74 p.cent of the patients. Treatment failures were recorded in 26 p.cent. The mean dosage of acebutolol was 10 mg/kg (maximum 22 mg/kg) and the drug was very well tolerated. Hypertension with an increased cardiac index and reno-vascular hypertension with increased plasma renin activity are good indications for acebutolol.
在一项为期一年的开放性治疗试验中,50名高血压患者单独服用β受体阻滞剂醋丁洛尔,或与其他降压药联合使用。74%的患者治疗效果被认为良好或中等。26%的患者记录为治疗失败。醋丁洛尔的平均剂量为10毫克/千克(最大剂量22毫克/千克),该药物耐受性良好。心脏指数升高的高血压和血浆肾素活性升高的肾血管性高血压是醋丁洛尔的良好适应证。