热放疗联合蛋白水解抑制剂（康瑞保）治疗头颈癌。
Thermoradiotherapy combined with a proteolysis inhibitor (contrical) in the treatment of head and neck cancer.
作者信息
Mikhalkin I A, Iashvili Z G, Bykov V L
机构信息
Division of Oncology, Kiev Research Institute of Otolaryngology, Ukraine.
出版信息
Oncology. 1993 Sep-Oct;50(5):344-7. doi: 10.1159/000227207.
For the prophylaxis of head and neck cancer recurrence and metastases we used radiation therapy, microwave hyperthermia and adjuvant therapy (inhibitor of proteolysis contrical and alpha-interferon). One hundred forty patients with primary cancer were treated. After 1 year of observation time and absence of tumor the patients were examined once every 3 months. The use of contrical and interferon combined with radiation therapy and microwave hyperthermia increased the 3-year survival rate by 37%, the number of patients without recurrence by 39% and decreased the appearance of regional metastases to 8.4%. Adjuvant therapy is discussed.
为预防头颈部癌症复发和转移，我们采用了放射治疗、微波热疗和辅助治疗（蛋白水解控制抑制剂和α-干扰素）。对140例原发性癌症患者进行了治疗。观察1年后无肿瘤，此后患者每3个月检查一次。使用蛋白水解控制抑制剂和干扰素联合放射治疗及微波热疗，使3年生存率提高了37%，无复发患者数量增加了39%，并将局部转移的发生率降至8.4%。文中对辅助治疗进行了讨论。
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