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[在处理与社会状况相关问题的特殊诊所就诊人群中的丙型肝炎病毒感染情况]

[Hepatitis C virus infections among persons attending special clinics dealing with problems related to social conditions].

作者信息

Rollag H, Thorvaldsen J, Kittelsen P, Bjøro K, Frøland S

机构信息

Bakteriologisk institutt Rikshospitalet, Oslo.

出版信息

Tidsskr Nor Laegeforen. 1993 Aug 20;113(19):2397-400.

PMID:7690995
Abstract

We have studied the prevalence of hepatitis C virus antibodies among 526 persons who attended an HIV diagnostic and counselling clinic and a clinic for sexually transmitted diseases in Oslo, Norway, during a 4-month period in early 1990. Possible risk factors for contracting hepatitis C virus infection were analysed and compared with results of the anti-hepatitis C virus test. The over-all prevalence rate of positive anti-hepatitis C virus tests was 7%. The prevalence rate was highest, 70%, among intravenous drug users (26/37). When intravenous drug users were excluded, only 2% of the remaining 484 persons had antibodies to hepatitis C virus. Among persons with no history of intravenous drug use, a positive correlation was found among women between the presence of hepatitis C virus antibodies and previous gonorrhoea. Male homosexual activity did not correlate with the presence of hepatitis C virus infection. Neither the number of heterosexual partners, nor sex with intravenous drug users, correlated with the presence of hepatitis C virus antibodies. Thus, according to our study the overwhelming risk factor for contracting hepatitis C virus infection was intravenous drug use.

摘要

1990年初的4个月期间,我们对挪威奥斯陆一家艾滋病毒诊断与咨询诊所及一家性传播疾病诊所的526名就诊者进行了丙型肝炎病毒抗体流行情况研究。分析了感染丙型肝炎病毒的可能危险因素,并与抗丙型肝炎病毒检测结果进行了比较。抗丙型肝炎病毒检测呈阳性的总体流行率为7%。在静脉注射吸毒者中流行率最高,为70%(26/37)。排除静脉注射吸毒者后,其余484人中只有2%的人有丙型肝炎病毒抗体。在无静脉注射吸毒史的人群中,女性的丙型肝炎病毒抗体阳性与既往淋病感染之间存在正相关。男性同性恋行为与丙型肝炎病毒感染无关。异性性伴侣的数量以及与静脉注射吸毒者发生性行为,均与丙型肝炎病毒抗体无关。因此,根据我们的研究,感染丙型肝炎病毒的主要危险因素是静脉注射吸毒。

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