Múñoz A, de Boer-Van Huizen R, Bergervoet-Vernooy I, ten Donkelaar H J
Department of Anatomy and Embryology, University of Nijmegen, The Netherlands.
Brain Res Dev Brain Res. 1993 Aug 20;74(2):291-4. doi: 10.1016/0165-3806(93)90016-4.
In Xenopus laevis fluorescent dextran amines were applied to study the development of the dorsal column-medial lemniscal projection: rhodamine dextran amine was applied at the mesodiencephalic border to retrogradely label the cells of origin of the medial lemniscus in the dorsal column nucleus (DCN); fluorescein dextran amine to the spinal cord to anterogradely label the primary afferent projections to the DCN. The first mesodiencephalic projections were found at stage 51, i.e. almost immediately after spinal afferent fibers had reached the DCN.
在非洲爪蟾中，应用荧光葡聚糖胺来研究背柱-内侧丘系投射的发育：将罗丹明葡聚糖胺应用于中脑间脑边界，以逆行标记背柱核（DCN）中内侧丘系的起源细胞；将荧光素葡聚糖胺应用于脊髓，以顺行标记至DCN的初级传入投射。在第51期发现了第一批中脑间脑投射，即几乎在脊髓传入纤维到达DCN之后立即发现。
