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[良性前列腺增生——老年患者的治疗选择]

[Benign prostatic hyperplasia--choice of therapy in the elderly].

作者信息

Schultze-Seemann W

机构信息

Urologische Abteilung, Universität Freiburg.

出版信息

Fortschr Med. 1993 Sep 10;111(25):394-7.

PMID:7691697
Abstract

The incidence of benign prostatic hyperplasia of up to 80% in 80-year-old men raises question as to possible therapeutic consequences. For decades, the standard treatment has consisted in transurethral resection of the prostate (TUR-P) which results in subjective and objective improvement in up to 95% of the cases and has low morbidity and negligible mortality. With a view to establishing a minimally invasive form of treatment, the search for alternative therapies makes good sense. To date, however, various medical therapeutic approaches (phytotherapy, alpha-blockers, antiandrogens, 5-alpha-reductase inhibitors) and/or interventional measures (thermotherapy, stents, balloon dilatation) have failed to match the therapeutic efficacy of TUR. However, in individuals at a high risk of surgery, they represent practicable alternatives.

摘要

80岁男性良性前列腺增生的发病率高达80%,这引发了对可能的治疗后果的质疑。几十年来,标准治疗方法一直是经尿道前列腺切除术(TUR-P),该方法在高达95%的病例中能带来主观和客观上的改善,且发病率低、死亡率可忽略不计。为了建立一种微创治疗方式,寻找替代疗法是很有意义的。然而,迄今为止,各种医学治疗方法(植物疗法、α受体阻滞剂、抗雄激素药物、5α还原酶抑制剂)和/或介入措施(热疗、支架、球囊扩张)都未能达到TUR的治疗效果。不过,对于手术风险高的患者,它们是可行的替代方案。

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