Type D SRV-2 virus-specific CD8+ and CD4- CD8- T cells that regulate virus-induced T cell proliferation in Celebes macaques.
作者信息
Malley A, Pangares N, Mayo S K, Zeleny-Pooley M, Torres J V, Benjamin E, Axthelm M K
机构信息
Oregon Regional Primate Research Center, Beaverton 97006.
出版信息
J Med Primatol. 1993 Feb-May;22(2-3):80-5.
PMID:7692057
Abstract
These studies defined SRV-2 envelope peptides 96-102, 127-152, and 233-249 as T cell epitopes that induce significant T cell proliferation. Peripheral blood lymphocytes of Celebes macaques (Macaca nigra) exposed to SRV-2 and currently virus- antibody+, cultured with SRV-2 virus show strongly suppressed T cell responses and have two immunoregulatory T cell populations.
摘要
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