Toledo-Pereyra L H, Simmons R L, Olson L C, Najarian J S
Surgery. 1976 Apr;79(4):377-83.
Perfusion of cadaver kidneys up to 48 hours did not adversely affect the long-term renal allotransplant function and did not result in an increased rate of rejection. In fact, cadaver kidneys perfused for longer periods of time had a slightly better functional survival rate than did kidneys perfused for shorter periods. From 100 perfused cadaver kidneys, we can conclude that the length of perfusion had little if any effect on the immunogenicity of the renal allograft in the immunosuppressed transplant patient.
对尸体肾进行长达48小时的灌注,对长期肾同种异体移植功能没有不利影响,也不会导致排斥率增加。事实上,灌注时间较长的尸体肾的功能存活期略长于灌注时间较短的肾脏。从100个灌注的尸体肾来看,我们可以得出结论,灌注时间对免疫抑制移植患者肾移植物的免疫原性几乎没有影响。