一名患有家族性基底节钙化和血清甲胎蛋白升高患者的松果体节细胞胶质瘤：病例报告

Pineal ganglioglioma in a patient with familial basal ganglia calcification and elevated serum alpha-fetoprotein: case report.

作者信息

Tokoro K, Chiba Y, Ohtani T, Abe H, Yagishita S

机构信息

Department of Neurosurgery, Kanagawa Rehabilitation Center, Japan.

出版信息

Neurosurgery. 1993 Sep;33(3):506-11; discussion 511. doi: 10.1227/00006123-199309000-00023.

DOI:10.1227/00006123-199309000-00023

PMID:7692346

Abstract

Pineal ganglioglioma was diagnosed in a 36-year-old man with familial basal ganglia calcification and elevated serum alpha-fetoprotein. The patient was treated surgically with a good result. Only four other cases of this tumor have been reported. His 38-year-old brother also showed basal ganglia calcification and elevated serum chorionic gonadotropin as well as alpha-fetoprotein. Familial basal ganglia calcification with elevated serum alpha-fetoprotein in a nonhepatic benign condition is rare. The pathogenesis of these conditions is discussed.

摘要

一名36岁患有家族性基底节钙化和血清甲胎蛋白升高的男性被诊断为松果体节细胞胶质瘤。该患者接受了手术治疗，效果良好。此前仅报道过另外4例这种肿瘤。他38岁的哥哥也表现出基底节钙化以及血清绒毛膜促性腺激素和甲胎蛋白升高。在非肝脏良性疾病中出现家族性基底节钙化并伴有血清甲胎蛋白升高的情况很罕见。本文对这些病症的发病机制进行了讨论。