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First-trimester free beta (hCG) screening for Down syndrome.

作者信息

Macri J N, Spencer K, Aitken D, Garver K, Buchanan P D, Muller F, Boue A

机构信息

NTD Laboratories Inc., Carle Place, NY 11514.

出版信息

Prenat Diagn. 1993 Jul;13(7):557-62. doi: 10.1002/pd.1970130704.

DOI:10.1002/pd.1970130704
PMID:7692430
Abstract

Maternal serum free beta (hCG) levels are elevated (median 2.20 MOM) in the first trimester of pregnancy in 38 Down syndrome cases as compared with appropriate controls. This observation may form the basis for its use as a marker in screening for Down syndrome in the first trimester. Altered levels of the free beta analyte are observed in pregnancy conditions or complications other than Down syndrome.

摘要

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