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[烟曲霉菌孢子导致小鼠和豚鼠的实验性流产]

[Experimental abortions in mice and guinea pigs caused by Aspergillus fumigatus spores].

作者信息

Venev S

出版信息

Vet Med Nauki. 1976;13(1):86-93.

PMID:769306
Abstract

Experiments were carried out with a total of 82 laboratory animals including 56 mice and 26 guinea pigs. The possibility was tested to provoke abortions in them with the use of Aspergillus fumigatus spores introduced through the trachea, orally or vaginally. The mould was isolated on Chapek agar from an aborted bovine fetus. It was found that all three routes of infection lead to abortions setting in after three to five treatments on the 1st to 3rd day following the last introduction of spores. The pregnant mice and guinea pigs showed individual sensitivity to the infection.

摘要

对总共82只实验动物进行了实验,其中包括56只小鼠和26只豚鼠。测试了通过气管、口服或阴道引入烟曲霉菌孢子诱发它们流产的可能性。该霉菌是从一头流产的牛胎儿中在查氏琼脂上分离出来的。结果发现,所有三种感染途径都会在最后一次引入孢子后的第1至3天经过三到五次处理后导致流产。怀孕的小鼠和豚鼠对感染表现出个体敏感性。

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