Gioglio L
Istituto di Anatomia Umana Normale, Università di Pavia, Italy.
Eur J Histochem. 1993;37(3):249-56.
The effects of cytochalasin B on the three types of secreting cells (apical, paracoronal and parietal cells) present in the fungiform papilla of the frog's tongue were studied. Cytochalasin B induced morphological modifications only in the apical secreting cells, localized in the sensorial area, without affecting the paracoronal cells or the parietal cells. The morphological features of treated apical cells showed that the drug induces two different effects: a disappearance of microfilaments and an increase in the exocytotic process. The results are related to previous experimental findings which showed that cytochalasin B produces actin depolymerization and interferes with calcium transport.
研究了细胞松弛素B对蛙舌菌状乳头中存在的三种分泌细胞（顶端细胞、冠周细胞和壁细胞）的影响。细胞松弛素B仅在位于感觉区域的顶端分泌细胞中诱导形态学改变，而不影响冠周细胞或壁细胞。经处理的顶端细胞的形态学特征表明，该药物诱导了两种不同的效应：微丝消失和胞吐过程增加。这些结果与先前的实验结果相关，先前的实验结果表明细胞松弛素B会导致肌动蛋白解聚并干扰钙转运。
