颅咽管瘤的免疫组织化学研究
Immunohistochemical study of craniopharyngiomas.
作者信息
Kubo O, Tajika Y, Uchimuno H, Muragaki Y, Shimoda M, Hiyama H, Morishita K, Takakura K
机构信息
Department of Neurosurgery, Tokyo Women's Medical College.
出版信息
Noshuyo Byori. 1993;10(2):131-4.
The purpose of this study is to present the histological characteristics of tumor origin and proliferative characteristics of craniopharyngioma. In 25 craniopharyngiomas, the immunoperoxidase technique revealed strong positive reactions for keratin and cytokeratin in cytoplasm of tumor cells. But, immunostaining of keratin and cytokeratin differ from each of layer of craniopharyngioma. The ciliated epithelium in the craniopharyngioma was not stained by keratin, but ciliated epithelium of Rathke's cleft cyst was stained by cytokeratin.
本研究的目的是呈现颅咽管瘤的肿瘤起源组织学特征和增殖特征。在25例颅咽管瘤中，免疫过氧化物酶技术显示肿瘤细胞胞质对角蛋白和细胞角蛋白呈强阳性反应。但是，角蛋白和细胞角蛋白的免疫染色在颅咽管瘤的各层中有所不同。颅咽管瘤中的纤毛上皮未被角蛋白染色，而拉克囊囊肿的纤毛上皮被细胞角蛋白染色。
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