Ono H, Tamai S, Yajima H, Fukui A, Inada Y, Mizumoto S
Department of Orthopaedic Surgery, Nara Medical University, Japan.
Br J Plast Surg. 1993 Sep;46(6):449-55. doi: 10.1016/0007-1226(93)90216-x.
Prefabricated flaps were created by femoral vessel implantation beneath the abdominal skin in rabbits. The area of survival and blood flow through the prefabricated flap were measured after 1, 2, 4, 6, 8, and 12-week intervals. The parameters at 6, 8 and 12-week intervals were significantly larger than those for random pattern flaps (p < 0.01), but were significantly smaller than those for axial pattern flaps (p < 0.01). The minimum interval at which the prefabricated flap could be transferred successfully was between 6 and 8 weeks in this model. Microangiography demonstrated that neovascularisation began at the distal end of the implanted vascular bundle and spread throughout the flap by 8 weeks.
通过将股血管植入兔腹部皮肤下制作预制皮瓣。在1、2、4、6、8和12周的时间间隔后，测量预制皮瓣的存活面积和血流量。6、8和12周时间间隔时的参数显著大于随意型皮瓣（p < 0.01），但显著小于轴型皮瓣（p < 0.01）。在该模型中，预制皮瓣能够成功转移的最短时间间隔在6至8周之间。微血管造影显示，新生血管形成始于植入血管束的远端，并在8周时遍布整个皮瓣。
