Jacobs B L, Fornal C A
Dept of Psychology, Princeton University, NJ 08544.
Trends Neurosci. 1993 Sep;16(9):346-52. doi: 10.1016/0166-2236(93)90090-9.
The activity of 5-HT-containing neurons in the brain is activated preferentially in association with motor output in cats. This is especially apparent during changes in muscle tone and during responses mediated by central pattern generators; such as chewing, locomotion and respiration. These and other data support the hypothesis that the primary functions of the 5-HT system in the brain are to facilitate motor output and concurrently inhibit sensory information processing. This hypothesis is applicable phylogenetically, from invertebrates to mammals.
猫脑中含5-羟色胺（5-HT）的神经元活动优先与运动输出相关联而被激活。这在肌肉张力变化期间以及由中枢模式发生器介导的反应（如咀嚼、运动和呼吸）中尤为明显。这些及其他数据支持这样一种假说，即脑内5-HT系统的主要功能是促进运动输出并同时抑制感觉信息处理。这一假说在系统发育上适用，从无脊椎动物到哺乳动物。
