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纵隔镜检查阳性的支气管癌。219例病例回顾(作者译)

[Bronchial carcinoma with positive mediastinoscopy. Review of 219 cases (author's transl)].

作者信息

Labeeu F

出版信息

Acta Chir Belg. 1976 Mar;75(2):161-86.

PMID:769458
Abstract

Mediastinoscopy was positive in 219 out of 605 cases of bronchial carcinoma (36.2%). The author analyses the age, sex, location of primitive tumor, histology, distribution of positive nodes and treatment used. Data on node involvement confirms the high malignity of the oat-cell carcinoma: though one of the rarest, this form accounts for 40% of mediastinal involvements. The data also confirm the lymphatic drainage of right side tumors (4% of crossing over) and the bilateral drainage of left side tumors (37% of crossing over). The proportion of involved nodes is 73%. In the 20 cases where surgical resection was performed this proportion is 58% and the involved nodes are largely located in the lower portion of the accessible mediastinum. Survival curves are drawn according to various parameters (location, histology, treatment). Review of the literature yields some general conclusions on the operability of bronchial carcinoma. According to belgian statistics bronchial carcinoma is the leading cause of death from cancer in the male. Probable survival for patients with positive mediastinoscopy is 7.5 months, extending from 4 months in untreated cases to 12 months after radio-chemotherapy. Prognosis was best in the 16 patients who survived the immediate postoperative period.

摘要

在605例支气管癌病例中,219例(36.2%)纵隔镜检查结果为阳性。作者分析了患者的年龄、性别、原发肿瘤位置、组织学类型、阳性淋巴结分布及所采用的治疗方法。有关淋巴结受累的数据证实了燕麦细胞癌的高度恶性:尽管这是最罕见的类型之一,但这种类型占纵隔受累病例的40%。数据还证实了右侧肿瘤的淋巴引流(4%交叉)和左侧肿瘤的双侧引流(37%交叉)。受累淋巴结的比例为73%。在接受手术切除的20例病例中,这一比例为58%,且受累淋巴结大多位于可及纵隔的下部。根据各种参数(位置、组织学类型、治疗方法)绘制了生存曲线。对文献的回顾得出了一些关于支气管癌可切除性的一般性结论。根据比利时的统计数据,支气管癌是男性癌症死亡的主要原因。纵隔镜检查阳性患者的可能生存期为7.5个月,从未经治疗病例的4个月到放化疗后的12个月不等。预后最好的是16例术后即刻存活的患者。

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