Johnson J G, Williams J B, Rabkin J G, Goetz R R, Remien R H
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York.
Am J Psychiatry. 1995 Apr;152(4):551-4. doi: 10.1176/ajp.152.4.551.
The prevalences of personality disorders among HIV-positive and HIV-negative homosexual men were compared, and the presence of personality disorders was related to axis I psychiatric disorders, psychiatric distress, and impaired functioning.
The subjects were 162 homosexual men who either were HIV seronegative (N = 52) or were seropositive and had absent to moderate physical symptoms (N = 110). Lifetime and current histories of DSM-III-R axis I disorders, current diagnoses of DSM-III-R personality disorders, and levels of anxiety, depression, hopelessness, and adaptive functioning were assessed.
In both the seropositive and seronegative groups, 19% of the study participants were diagnosed with personality disorders. The seropositive participants with personality disorders reported higher levels of psychiatric symptoms and poorer functioning than all participants without personality disorders, and they were over six times as likely as the seronegative participants without personality disorders to have current axis I disorders.
These findings indicate that HIV infection and personality disorders may interactively increase the likelihood of clinically significant psychiatric symptoms.
比较HIV阳性和HIV阴性同性恋男性中人格障碍的患病率，并探讨人格障碍的存在与I轴精神障碍、精神痛苦及功能受损之间的关系。
研究对象为162名同性恋男性，其中HIV血清学阴性者52名，血清学阳性且身体症状轻微至中度者110名。评估了DSM-III-R I轴障碍的终生及当前病史、DSM-III-R人格障碍的当前诊断以及焦虑、抑郁、绝望和适应功能水平。
血清学阳性组和血清学阴性组中，均有19%的研究参与者被诊断为人格障碍。患有人格障碍的血清学阳性参与者报告的精神症状水平更高，功能更差，与所有未患人格障碍的参与者相比，他们患当前I轴障碍的可能性是未患人格障碍的血清学阴性参与者的六倍多。
这些发现表明，HIV感染和人格障碍可能相互作用，增加出现具有临床意义的精神症状的可能性。
