Voûte P D, Zock J P, Brunekreef B, de Jongste J C
Department of Epidemiology and Public Health, University of Wageningen, The Netherlands.
Allergy. 1994 Oct;49(9):724-9. doi: 10.1111/j.1398-9995.1994.tb02094.x.
The hypothesis was tested that wall-to-wall carpets on school classroom floors have a negative effect on the respiratory health of asthmatic children. Asthmatic patients (n = 98) were selected from the records of the Sophia Children's Hospital in Rotterdam. The patients were between 5 and 11 years old. All children had peak-flow measurements three times a day for a 1-month period. The parents of the children completed a diary in which respiratory symptoms and medication use were recorded daily for the same period. Dust samples were taken from classroom floors, living-room and bedroom floors, and mattresses of the children. The dust samples were analyzed for Der p I content, the major allergen of the house-dust mite Dermatophagoides pteronyssinus. The results of the study showed that there was no significant difference between children visiting schools with or without carpeted classroom floors in peak-flow variability, acute respiratory symptoms, or medication use. The Der p I content of dust collected from classroom floors was much lower than of dust collected from homes. There was a significant correlation between peak-flow variability and mattress dust Der p I content in asthmatic children sensitized to dust mites, but not between peak-flow variability and classroom floor dust Der p I content. We concluded that carpeted classroom floors do not contribute to asthma symptom severity, possibly because of the low levels of Der p I on them.
研究人员对一项假设进行了验证，即学校教室地面铺设的满铺地毯会对哮喘儿童的呼吸健康产生负面影响。研究人员从鹿特丹索菲亚儿童医院的记录中选取了哮喘患者（n = 98）。这些患者年龄在5至11岁之间。所有儿童在1个月的时间里每天进行3次峰值流量测量。孩子们的父母完成了一本日记，在日记中记录了同一时期内孩子每日的呼吸道症状和药物使用情况。研究人员从教室地面、客厅和卧室地面以及孩子们的床垫上采集了灰尘样本。对灰尘样本进行分析，检测屋尘螨（粉尘螨）的主要过敏原Der p I的含量。研究结果表明，在峰值流量变异性、急性呼吸道症状或药物使用方面，就读于教室地面有地毯和无地毯学校的儿童之间没有显著差异。从教室地面收集的灰尘中Der p I的含量远低于从家中收集的灰尘。在对尘螨敏感的哮喘儿童中，峰值流量变异性与床垫灰尘中Der p I的含量之间存在显著相关性，但与教室地面灰尘中Der p I的含量之间不存在显著相关性。我们得出结论，教室地面铺设地毯不会导致哮喘症状加重，这可能是因为地毯上Der p I的含量较低。
