N-甲基-N-亚硝基脲在肝脏复制性DNA中显示出与细胞周期相关的瞬时序列。
N-methyl-N-nitrosourea evidences cell cycle associated transient sequences in hepatic replicating DNA.
作者信息
Kanduc D
机构信息
Department of Biochemistry and Molecular Biology, Faculty of Science, University of Bari, Italy.
出版信息
Biochem Biophys Res Commun. 1995 Mar 17;208(2):506-10. doi: 10.1006/bbrc.1995.1367.
PMID:7695600
Abstract
Experiments of molecular hybridization were carried out with the aim of singling out DNA sequences which might be important in the hepatocarcinogenic action of N-methyl-N-nitrosourea. Results were obtained suggesting the synthesis of transitory DNA sequences during compensatory cell proliferation.
摘要
进行了分子杂交实验，目的是筛选出可能在N-甲基-N-亚硝基脲的致癌作用中起重要作用的DNA序列。结果表明在代偿性细胞增殖过程中会合成短暂的DNA序列。
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