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用于右心室-肺动脉管道的尺寸缩小的低温保存肺动脉瓣同种异体移植物:技术改进与功能评估

Size-reduced cryopreserved pulmonary valve allograft for an RV-PA conduit: technical modification and functional evaluation.

作者信息

Kitamura S, Kawachi K, Niwaya K, Fukutomi M, Kobayashi S, Hasegawa J, Kawata T, Sakaguchi H

机构信息

Department of Surgery III, Nara Medical College, Japan.

出版信息

J Card Surg. 1995 Jan;10(1):14-20. doi: 10.1111/j.1540-8191.1995.tb00584.x.

DOI:10.1111/j.1540-8191.1995.tb00584.x
PMID:7696784
Abstract

Cryopreserved pulmonary allografts harvested from adults at the time of kidney donation were size reduced and used in two children with pulmonary atresia and ventricular septal defect. A technical modification for the creation of size-reduced pulmonary allograft conduits is described. Postoperative ultrasonic and cineangiographic assessments revealed excellent function of the pulmonary bicuspid valved conduit with a minimal pressure gradient and essentially no regurgitation. Although the long-term fate of cryopreserved bicuspid pulmonary valve and conduit is unknown, this conduit provides excellent handling characteristics that render allograft conduits preferable to synthetic conduits. In addition, the remodeled bicuspid pulmonary allograft conduits have exhibited excellent hemodynamic characteristics and are a reasonable alternative to other types of conduits when an appropriate size allograft is not available.

摘要

从成年肾供体处获取的低温保存的肺同种异体移植物经尺寸缩小后,用于两名患有肺动脉闭锁和室间隔缺损的儿童。本文描述了一种用于制作尺寸缩小的肺同种异体移植管道的技术改良方法。术后超声心动图和心血管造影评估显示,带双叶肺动脉瓣的移植管道功能良好,压力阶差极小,且基本无反流。尽管低温保存的双叶肺动脉瓣和管道的长期转归尚不清楚,但这种管道具有出色的操作特性,使得同种异体移植管道比人工合成管道更具优势。此外,重塑后的双叶肺同种异体移植管道展现出优异的血流动力学特性,在无法获得合适尺寸同种异体移植物时,是其他类型管道的合理替代选择。

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引用本文的文献

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Mid- to long-term outcomes of cardiovascular tissue replacements utilizing homografts harvested and stored at Japanese institutional tissue banks.利用日本机构组织库采集和储存的同种移植物进行心血管组织替代的中期至长期结果。
Surg Today. 2011 Apr;41(4):500-9. doi: 10.1007/s00595-010-4459-x. Epub 2011 Mar 23.