Jalan R, Redhead D N, Hayes P C
Royal Infirmary of Edinburgh, United Kingdom.
Natl Med J India. 1995 Jan-Feb;8(1):15-21.
The transjugular intrahepatic portosystemic stent shunt (TIPSS) is essentially a side-to-side portocaval shunt performed by interventional radiological methods which connects the hepatic vein to the portal vein via the liver parenchyma. It can be performed successfully in 85% to 95% patients. The procedure mortality is low (1% to 2%) and is mainly from intraperitoneal bleeding. Major indications for TIPSS are in patients in whom sclerotherapy for bleeding varices has failed, those who have recurrent variceal haemorrhage after sclerotherapy or band ligation and in patients with refractory ascites, hypersplenism and portal gastropathy. It has also been used in some patients with the Budd-Chiari syndrome, portal vein thrombosis and cirrhotic hydrothorax. TIPSS is followed by variceal rebleeding and encephalopathy in about 10% to 20% of cases, deterioration in liver function in about 25% to 35% and shunt dysfunction in 15% to 60%. Further research should be directed at developing newer types of stents to prevent shunt dysfunction.
经颈静脉肝内门体分流术(TIPSS)本质上是一种通过介入放射学方法进行的侧侧门腔分流术,它经肝实质将肝静脉与门静脉相连。该手术在85%至95%的患者中可成功实施。手术死亡率较低(1%至2%),主要原因是腹腔内出血。TIPSS的主要适应证包括静脉曲张出血硬化治疗失败的患者、硬化治疗或套扎术后复发性静脉曲张出血的患者以及难治性腹水、脾功能亢进和门静脉性胃病患者。它也用于一些布加综合征、门静脉血栓形成和肝硬化性胸腔积液患者。TIPSS术后约10%至20%的病例会出现静脉曲张再出血和肝性脑病,约25%至35%的患者肝功能恶化,15%至60%的患者分流功能障碍。进一步的研究应致力于开发新型支架以预防分流功能障碍。